Dengue fever natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Dengue fever generally lasts a week or more, and can rarely be complicated by bleeding, febrile convulsions and coma. The prognosis is good. Dengue fever can be life-threatening in people with chronic diseases such as diabetes and asthma.

Natural History

  • Dengue fever generally lasts about six to seven days, with a smaller peak of fever at the trailing end of the fever (the so-called "biphasic pattern"). The platelet count will drop until the patient's temperature is normal.[1]

Complications

Possible complications of Dengue fever include:[2]

Prognosis

Although uncomfortable, dengue fever is generally not deadly.[1]. Mortality rates between 0% and 5.4% have been reported.[5][6] Dengue fever can be life-threatening in people with chronic diseases such as diabetes and asthma.

References

  1. 1.0 1.1 "Dengue: guidelines for diagnosis, treatment, prevention and control" (PDF).
  2. Halstead SB (2007). "Dengue". Lancet. 370 (9599): 1644–52. doi:10.1016/S0140-6736(07)61687-0. PMID 17993365.
  3. Wang CC, Liu SF, Liao SC, Lee IK, Liu JW, Lin AS; et al. (2007). "Acute respiratory failure in adult patients with dengue virus infection". Am J Trop Med Hyg. 77 (1): 151–8. PMID 17620647.
  4. Puccioni-Sohler M, Orsini M, Soares CN (2012). "Dengue: a new challenge for neurology". Neurol Int. 4 (3): e15. doi:10.4081/ni.2012.e15. PMC 3555217. PMID 23355928.
  5. Guzmán MG, Kourí G (2002). "Dengue: an update". Lancet Infect Dis. 2 (1): 33–42. PMID 11892494.
  6. Ong A, Sandar M, Chen MI, Sin LY (2007). "Fatal dengue hemorrhagic fever in adults during a dengue epidemic in Singapore". Int J Infect Dis. 11 (3): 263–7. doi:10.1016/j.ijid.2006.02.012. PMID 16899384.