Cutaneous receptor

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A cutaneous receptor is a type of sensory receptor found in the dermis or epidermis. These include Nociceptors (pain), Ruffini's end organ (sustained pressure), Meisner's corpuscle (changes in texture, slow vibrations), Pacinian corpuscle (deep pressure, fast vibrations), End-bulb of Krause, and Merkel's disc (sustained touch and pressure).


Types

Morphology

Cutaneous receptors are at the ends of afferent neurons. They are usually encapsulated in elaborate cellular corpuscles. Generally, they are linked to collagen-fibre networks within the capsule. Ion channels are situated near these networks.

In sensory transduction, the afferent nerves transmit through a series of synapses in the central nervous system, first in the spinal cord or trigeminal nucleus, depending on the dermatomic area concerned. One pathway then proceeds to the ventrobasal portion of the thalamus, and then on to the somatosensory cortex.


Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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