Codoxime

Codoxime
Clinical data
Synonyms	Codoxime
Identifiers
	IUPAC name (((4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-ylidene)amino)oxy)acetic acid;
CAS Number	7125-76-0;
PubChem CID	9570253;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C20H24N2O5
Molar mass	372.415 g/mol
3D model (JSmol)	Interactive image;
	SMILES CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3/C(=N/OCC(=O)O)/CC4;

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Codoxime is an opiate analogue that is an derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects^[1] and was found to have moderate potential to cause dependence in animal studies.^[2]

References

↑ Jack Fishman. Morphinone and Codeinone Derivatives. US Patent 3153042
↑ Jasinski DR, Martin WR. Assessment of the dependence-producing properties of dihydrocodeinone and codoxime. Clinical Pharmacology and Therapeutics. 1967 Mar-Apr;8(2):266-70. PMID 6021586

Template:Opioids

Template:WikiDoc Sources

[1] Jack Fishman. Morphinone and Codeinone Derivatives. US Patent 3153042

[2] Jasinski DR, Martin WR. Assessment of the dependence-producing properties of dihydrocodeinone and codoxime. Clinical Pharmacology and Therapeutics. 1967 Mar-Apr;8(2):266-70. PMID 6021586

[1]

[2]

Codoxime

Overview

References

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