Cefotiam
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| Cefotiam
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| Systematic (IUPAC) name | |
| (6R,7R)-7-{[2-(2-amino-1,3-thiazol-4-yl)acetyl] amino}-3-{[1-(2-dimethylaminoethyl)tetrazol-5-yl] sulfanylmethyl}-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid | |
| Identifiers | |
| CAS number | |
| ATC code | J01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C18H23N9O4S3 |
| Mol. mass | 525.631 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 60% (intramuscular) |
| Protein binding | 40% |
| Metabolism | Nil |
| Half life | Approximately 1 hour |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Intravenous, intramuscular |
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Directions to Hospitals Treating Cefotiam Risk calculators and risk factors for Cefotiam
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Cefotiam is a second-generation cephalosporin antibiotic.
External links
- Müller R, Böttger C, Wichmann G (2003). "Suitability of cefotiam and cefuroxime axetil for the perioperative short-term prophylaxis in tonsillectomy patients.". Arzneimittelforschung 53 (2): 126-32. PMID 12642969.
- Kolben M, Mandoki E, Ulm K, Freitag K (2001). "Randomized trial of cefotiam prophylaxis in the prevention of postoperative infectious morbidity after elective cesarean section.". Eur J Clin Microbiol Infect Dis 20 (1): 40-2. PMID 11245321.
- Shimizu S, Chen K, Miyakawa S (1996). "Cefotiam-induced contact urticaria syndrome: an occupational condition in Japanese nurses.". Dermatology 192 (2): 174-6. PMID 8829507.
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