Neuronal acetylcholine receptor subunit alpha-10, also known as nAChRα10 and cholinergic receptor nicotinic alpha 10, is a protein that in humans is encoded by the CHRNA10gene.[1] The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).
This nAchR subunit is required for the normal function of the olivocochlear system which is part of the auditory system.[2] Furthermore, selective block of α9α10 nicotinic acetylcholine receptors by the conotoxin RgIA has been shown to be analgesic in an animal model of nerve injury pain.[3]
References
↑Lustig LR, Peng H, Hiel H, Yamamoto T, Fuchs PA (May 2001). "Molecular cloning and mapping of the human nicotinic acetylcholine receptor alpha10 (CHRNA10)". Genomics. 73 (3): 272–83. doi:10.1006/geno.2000.6503. PMID11350119.