Biliverdin reductase
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| biliverdin reductase A
| |
| Identifiers | |
| Symbol | BLVRA |
| Alt. Symbols | BLVR |
| Entrez | 644 |
| HUGO | 1062 |
| OMIM | 109750 |
| RefSeq | NM_000712 |
| UniProt | P53004 |
| Other data | |
| EC number | 1.3.1.24 |
| Locus | Chr. 7 p14-cen |
| biliverdin reductase B
| |
| Identifiers | |
| Symbol | BLVRB |
| Alt. Symbols | FLR |
| Entrez | 645 |
| HUGO | 1063 |
| OMIM | 600941 |
| RefSeq | NM_000713 |
| UniProt | P30043 |
| Other data | |
| EC number | 1.3.1.24 |
| Locus | Chr. 19 q13.1-13.2 |
Biliverdin reductase is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond.
Biliverdin.png
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External links
Oxidoreductases: CH-CH oxidoreductases (EC 1.3) | |
|---|---|
| 1.3.1. NAD/NADP acceptor | Enoyl-acyl carrier protein reductase/Enoyl ACP reductase - 7-Dehydrocholesterol reductase - Biliverdin reductase - 2,4 Dienoyl-CoA reductase |
| 1.3.3. Oxygen acceptor | Dihydroorotate dehydrogenase - Coproporphyrinogen III oxidase - Protoporphyrinogen oxidase - |
| 1.3.5. Quinone | Succinate - coenzyme Q reductase |
| 1.3.99. Other acceptors | Fumarate reductase - Butyryl CoA dehydrogenase - Acyl CoA dehydrogenase - 5-alpha reductase - Glutaryl-CoA dehydrogenase - Isovaleryl coenzyme A dehydrogenase |
Metabolism: Porphyrin enzymes | |
|---|---|
| Porphyrin biosynthesis | initial mitochondrial: Aminolevulinic acid synthase - Porphobilinogen synthase
cytosolic: Porphobilinogen deaminase - Uroporphyrinogen III synthase - Uroporphyrinogen III decarboxylase - Coproporphyrinogen III oxidase terminal mitochondrial: Protoporphyrinogen oxidase - Ferrochelatase |
| Heme breakdown to bile | spleen: Heme oxygenase - Biliverdin reductase liver: UDP-glucuronosyltransferase |
| see also disorders, intermediates | |
