Myelocyte
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A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow, but not in circulating blood (except when caused by certain diseases).
Histology
When stained with the usual dyes, the cytoplasm is distinctly basophilic and relatively more abundant than in myeloblasts or promyelocytes, even though myelocytes are smaller cells.
Numerous cytoplasmic granules are present in the more mature forms of myelocytes. Neutrophilic and eosinophilic granules are peroxidase-positive, while basophilic granules are not.
The nuclear chromatin is coarser than that observed in myeloblasts, but it is relatively faintly stained and lacks a well defined membrane.
The nucleus is fairly regular in contour (not indented), and seems to be 'buried' beneath the numerous cytoplasmic granules. (If the nucleus were indented, it would likely be a metamyelocyte.)
Precursor
Myeloblasts or blasts are new, immature blood cells developed in the bone marrow that are the precursors of myelocytes.
Measurement
There is an internationally agreed method of counting blasts, with results from M1 upwards.
Additional images
 Hematopoiesis |
References
External links
- Neutrophilic Myelocyte Presented by the University of Virginia
- Eosinophilic Myelocyte Presented by the University of Virginia
- Basophilic Myelocyte Presented by the University of Virginia
- Image at queensu.ca
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
