Adrenoleukodystrophy CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Overview

Brain CT scan may be helpful in the diagnosis of Adrenoleukodystrophy but not used as it is less sensitive than MRI. Findings on CT scan suggestive of Adrenoleukodystrophy can include Contrast enhancement within or adjacent to the abnormally hypodense deep white matter of the parietal, occipital lobes and at the interface between this active demyelinating area and uninvolved normal brain, Asymmetric areas of diminished attenuation in occipital horns of the lateral ventricles and the splenium of the corpus callosum.

CT

Brain CT scan may be helpful in the diagnosis of Adrenoleukodystrophy but not used as it is less sensitive than MRI. Findings on CT scan suggestive of Adrenoleukodystrophy can include:

  • Contrast enhancement within or adjacent to the abnormally hypodense deep white matter of the parietal, occipital lobes and at the interface between this active demyelinating area and uninvolved normal brain. [1][2]
  • Asymmetric areas of diminished attenuation in occipital horns of the lateral ventricles and the splenium of the corpus callosum.[2]

References

  1. Kumar AJ, Rosenbaum AE, Naidu S, Wener L, Citrin CM, Lindenberg R; et al. (1987). "Adrenoleukodystrophy: correlating MR imaging with CT". Radiology. 165 (2): 497–504. doi:10.1148/radiology.165.2.3659373. PMID 3659373.
  2. 2.0 2.1 Volkow ND, Patchell L, Kulkarni MV, Reed K, Simmons M (1987). "Adrenoleukodystrophy: imaging with CT, MRI, and PET". J Nucl Med. 28 (4): 524–7. PMID 3494828.

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