ADP-dependent short-chain-acyl-CoA hydrolase
- acyl-CoA + H2O CoA + a carboxylate
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is ADP-dependent-short-chain-acyl-CoA hydrolase. Other names in common use include short-chain acyl coenzyme A hydrolase, propionyl coenzyme A hydrolase, propionyl-CoA hydrolase, propionyl-CoA thioesterase, short-chain acyl-CoA hydrolase, and short-chain acyl-CoA thioesterase. It employs one cofactor, ADP. At least one compound, NADH is known to inhibit this enzyme.
- IUBMB entry for 22.214.171.124
- BRENDA references for 126.96.36.199 (Recommended.)
- PubMed references for 188.8.131.52
- PubMed Central references for 184.108.40.206
- Google Scholar references for 220.127.116.11
- Alexson SE, Nedergaard J (1988). "A novel type of short- and medium-chain acyl-CoA hydrolases in brown adipose tissue mitochondria". J. Biol. Chem. 263: 13564&ndash, 71. PMID 2901416.
- Alexson SE, Svensson LT, Nedergaard J (1989). "NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat". Biochim. Biophys. Acta. 1005: 13&ndash, 9. PMID 2570608.
- The CAS registry number for this enzyme class is 117698-16-5.
Gene Ontology (GO) codes
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