ACG guidelines classification scheme

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Overview

The GRADE system of quality of evidence and strength of recommendation gives insight into the confidence of the American College of Gastroenterology in the recommendation and the likelihood that further research would change said recommendation.[1]

Classification of Recommendation

GRADE system of quality of evidence and strength of recommendation:[1]

Quality of Evidence

GRADE Explanation
High Further research is very unlikely to change our confidence in the estimate of effect.
Moderate Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very Low Any estimate of the effect is very uncertain.

Strength of Recommendation

The strength of recommendation is determined based on a benefit vs. cost/risk to patient.

GRADE Explanation
Strong The desirable effects of an intervention clearly outweigh the undesirable effects or clearly do not.
Weak/Conditional/Discretionary The trade offs are less certain between the desirable and undesirable effects of an intervention.

References

  1. 1.0 1.1 Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P; et al. (2008). "GRADE: an emerging consensus on rating quality of evidence and strength of recommendations". BMJ. 336 (7650): 924–6. doi:10.1136/bmj.39489.470347.AD. PMC 2335261. PMID 18436948.

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