ACC AHA Guidelines Classification Scheme

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ACC AHA Guidelines Classification Scheme

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The Class designation is used to indicate whether a therapy is recommended or not and the certainty surrounding that recommendation.

Classification of Recommendations

  • Class I: Conditions for which there is evidence and/or general agreement that a given procedure or treatment is beneficial, useful, and effective.
  • Class II: Conditions for which there is conflicting evidence and/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment.
  • Class IIa: Weight of evidence/opinion is in favor of usefulness/efficacy.
  • Class IIb: Usefulness/efficacy is less well established by evidence/opinion.
  • Class III: Conditions for which there is evidence and/or general agreement that a procedure/treatment is not useful/effective and in some cases may be harmful.

Use the Level of Evidence designation to indicate the strength of the data associated with that recommendation.

Level of Evidence

  • Level of Evidence A: Data derived from multiple randomized clinical trials or meta-analyses.
  • Level of Evidence B: Data derived from a single randomized trial, or nonrandomized studies.
  • Level of Evidence C: Only consensus opinion of experts,case studies, or standard-of-care.

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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .