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In enzymology, a 3-deoxy-manno-octulosonate-8-phosphatase (EC is an enzyme that catalyzes the chemical reaction

3-deoxy-D-manno-octulosonate 8-phosphate + H2O 3-deoxy-D-manno-octulosonate + phosphate

Thus, the two substrates of this enzyme are 3-deoxy-D-manno-octulosonate 8-phosphate and H2O, whereas its two products are 3-deoxy-D-manno-octulosonate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase. This enzyme participates in lipopolysaccharide biosynthesis.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
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  • Ray PH, Benedict CD (1980). "Purification and characterization of specific 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase from Escherichia coli B". J. Bacteriol. 142: 60&ndash, 8. PMID 6246070.

External links

The CAS registry number for this enzyme class is 59088-24-3.

Gene Ontology (GO) codes