1,2,4-Triazole

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Template:Chembox E numberTemplate:Chembox SolubilityInWater
1,2,4-Triazole
IUPAC name 1H-1,2,4-triazole
Other names 1,2,4-triazole pyrrodiazole
Identifiers
3D model (JSmol)
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Properties
C2H3N3
Molar mass 69.0654
Appearance white solid
Melting point
Boiling point
Acidity (pKa) 2.2
Basicity (pKb) 10.3
Hazards
Flash point {{{value}}}
Related compounds
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

1,2,4-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,4-Triazole is a basic aromatic heterocycle.

1,2,4-Triazoles can be prepared synthetically using the Einhorn-Brunner reaction in which an imide is reacted with an alkyl hydrazine to form a mixture of isomeric 1,2,4-triazoles.

1,2,4-Triazole derivatives find use in a wide variety of applications, most notably as antifungals such as fluconazole and itraconazole.

References


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