https://www.wikidoc.org/api.php?action=feedrecentchanges&days=3&feedformat=atom&hidebots=1&hideminor=1&urlversion=1 2026-05-04T13:18:34Z Track the most recent changes to the wiki in this feed. MediaWiki 1.45.1 https://www.wikidoc.org/index.php?title=Sandbox&diff=1744133&oldid=1744129 2026-05-03T18:30:46Z

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Muzamil Akhtar https://www.wikidoc.org/index.php?title=Ischemic_stroke_medical_therapy&diff=1744130&oldid=1732751 2026-05-03T15:59:28Z

<p><span class="autocomment">Overview</span></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:59, 3 May 2026</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l4">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Overview==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Overview==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">The medical therapy of [[</del>ischemic stroke<del style="font-weight: bold; text-decoration: none;">]] </del>is <del style="font-weight: bold; text-decoration: none;">mainly </del>directed to <del style="font-weight: bold; text-decoration: none;">fibrinolysis of clot by r-tPA </del>with in <del style="font-weight: bold; text-decoration: none;">3 to 4</del>.<del style="font-weight: bold; text-decoration: none;">5 </del>hours <del style="font-weight: bold; text-decoration: none;">of symptom </del>onset<del style="font-weight: bold; text-decoration: none;">. Acute treatment with antiplatelets may have a role if given within </del>24<del style="font-weight: bold; text-decoration: none;">-48 </del>hours <del style="font-weight: bold; text-decoration: none;">of stroke onset</del>. <del style="font-weight: bold; text-decoration: none;">Long term management with statins, </del>antiplatelets, <del style="font-weight: bold; text-decoration: none;">anticoagulants</del>, <del style="font-weight: bold; text-decoration: none;">antihypertensive and antidiabetic agents may help prevent the recurrence.&lt;ref&gt;{{cite journal |author=Hackam DG</del>, <del style="font-weight: bold; text-decoration: none;">Spence JD |title=Combining multiple approaches for the secondary prevention of vascular events after stroke: a quantitative modeling study |journal=Stroke |volume=38 |issue=6 |pages=1881–5 |year=2007 |pmid=17431209 |doi=10.1161/STROKEAHA.106.475525}}&lt;/ref&gt;</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Acute </ins>ischemic stroke <ins style="font-weight: bold; text-decoration: none;">therapy </ins>is <ins style="font-weight: bold; text-decoration: none;">primarily </ins>directed to <ins style="font-weight: bold; text-decoration: none;">rapid reperfusion with intravenous thrombolysis (alteplase or tenecteplase) in eligible patients and endovascular thrombectomy (EVT) in eligible patients </ins>with <ins style="font-weight: bold; text-decoration: none;">large vessel occlusion (LVO); these treatments should be considered </ins>in <ins style="font-weight: bold; text-decoration: none;">parallel and should not delay each other</ins>.</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Acute treatment to control blood pressure, blood glucose </del>and <del style="font-weight: bold; text-decoration: none;">fever may help prevent the complications and have a prognostic significance</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Antiplatelet therapy (usually aspirin) is recommended within 24–48 </ins>hours <ins style="font-weight: bold; text-decoration: none;">after </ins>onset <ins style="font-weight: bold; text-decoration: none;">in most patients who are not receiving IV thrombolysis, and is generally delayed until </ins>24 hours <ins style="font-weight: bold; text-decoration: none;">after thrombolysis</ins>.</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Secondary prevention includes </ins>antiplatelets <ins style="font-weight: bold; text-decoration: none;">or anticoagulation depending on etiology (eg</ins>, <ins style="font-weight: bold; text-decoration: none;">atrial fibrillation)</ins>, <ins style="font-weight: bold; text-decoration: none;">lipid-lowering therapy</ins>, and <ins style="font-weight: bold; text-decoration: none;">risk-factor management</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Medical Therapy==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Medical Therapy==</div></td></tr> </table>

Hasnain Ali https://www.wikidoc.org/index.php?title=Sandbox&diff=1744129&oldid=1744111 2026-05-03T14:43:03Z

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Muzamil Akhtar